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Publications
7361 publication(s) trouvée(s)
Article scientifique
Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential
The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells …
Article scientifique
Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans
BACKGROUND: The gene encoding a thermostable cellulase of family 12 was previously isolated from a Rhodothermus marinus through functional screening. …
Article scientifique
LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate
Masitinib (MST) is a selective tyrosine kinase inhibitor. Validated liquid chromatography tandem mass spectrometric method (LC–MS/MS) was developed for the …
Article scientifique
Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
Alzheimer’s disease (AD) is a neurodegenerative disorder associated with deficits in cognition and synaptic plasticity. While accumulation of amyloid β …
Article scientifique
Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts
African indigenous sheep are classified as fat-tail, thin-tail and fat-rump hair sheep. The fat-tail are well adapted to dryland environments, …
Article scientifique
A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country
Shigellosis is a mild-to-severe diarrheal infection caused by the genus Shigella and responsible for significant morbidity and mortality worldwide. We …
Article scientifique
Molecular cloning, sequence analysis and tissue expression of bovine imprinted ASCL2 gene
Achaete-scute like-2 (ASCL2) gene is a maternally expressed gene that encodes a lineage-specific transcription factor that is essential for neurectoderm …
Erratum
Corrigendum: Gene Expression in Class 2 Integrons Is SOS-Independent and Involves Two Pc Promoters
Corrigendum on: Jové T, Da Re S, Tabesse A, Gassama-Sow A and Ploy M-C (2017) Gene Expression in Class 2 …
Article scientifique
Hereditary Ichthyosis and Achieving the Oral Mucosa, Retrospective Study of 33 Cases
Ichthyosis is hereditary abnormalities of life-long keratinization. Clinical traits, mode of transmission and histological study allow the classification of most …
Article scientifique
Management of X-linked adrenoleukodystrophy in Morocco: actual situation
OBJECTIVES: X-linked adrenoleukodystrophy is a neurodegenerative disorder caused by mutations in the ABCD1 gene. Adrenomyeloneuropathy and childhood cerebral Adrenoleukodystrophy are …
Article scientifique
Ginsenoside Rg1 improves ischemic brain injury by balancing mitochondrial biogenesis and mitophagy
Purpose: To study the effects of ginsenoside Rg1 on mitochondrial dysfunction induced by ischemic stroke.Methods: Human neuroblastoma SK-N-SH cells, subjected …
Article scientifique
New variant identified in major susceptibility locus to tuberculosis on chromosomal region 8q12-q13 in Moroccan population: a case control study
BACKGROUND: Tuberculosis (TB) remains a global health problem. Several studies have implicated genetic host factors in predisposing populations to TB …
Article scientifique
Identifying accessible prognostic factors for breast cancer relapse: a case-study on 405 histologically confirmed node-negative patients
BACKGROUND: Histologically, node-negative breast cancer generally have a good prognosis. However, 10 to 30% of the cases present local relapses …
Article scientifique
PFI1785w: A highly conserved protein associated with pregnancy associated malaria
Pregnancy-associated malaria (PAM) is one of the severe forms of Plasmodium falciparum infection. The main antigen VAR2CSA is the target …
Article scientifique
Short tandem repeat (STR) based genetic diversity and relationship of indigenous Niger cattle
Abstract. The diversity of cattle in Niger is predominantly represented by three indigenous breeds: Zebu Arabe, Zebu Bororo and Kuri. …
Article scientifique
Differential distribution of Y-chromosome haplotypes in Swiss and Southern European goat breeds
The analysis of Y-chromosome variation has provided valuable clues about the paternal history of domestic animal populations. The main goal …
Article scientifique
Transcriptome analysis of WRKY gene family in Oryza officinalis Wall ex Watt and WRKY genes involved in responses to Xanthomonas oryzae pv. oryzae stress
Oryza officinalis Wall ex Watt, a very important and special wild rice species, shows abundant genetic diversity and disease resistance …
Article scientifique
Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review
BACKGROUND: It is now well-known that some antimalarials such as primaquine may induce severe hemolytic anemia in people with G-6-PD …
Article scientifique
Using path analysis to predict bodyweight from body measurements of goats and sheep of communal rangelands in Botswana
The objective of this study was to determine the practicality of using linear body measurement traits to predict live weight …
Article scientifique
Ethical considerations in forensic genetics research on tissue samples collected post-mortem in Cape Town, South Africa
BACKGROUND: The use of tissue collected at a forensic post-mortem for forensic genetics research purposes remains of ethical concern as …