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Publications
7361 publication(s) trouvée(s)
Article scientifique
Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway
Dietary polyphenols, derived from natural products, have received a great interest for their chemopreventive properties against cancer. In this study, …
Article scientifique
Virtual reality assisted microscopy data visualization and colocalization analysis
BACKGROUND: Confocal microscopes deliver detailed three-dimensional data and are instrumental in biological analysis and research. Usually, this three-dimensional data is …
Article scientifique
Impact of salt stress, cell death, and autophagy on peroxisomes: quantitative and morphological analyses using small fluorescent probe N-BODIPY
Plant peroxisomes maintain a plethora of key life processes including fatty acid β-oxidation, photorespiration, synthesis of hormones, and homeostasis of …
Article scientifique
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome
Nakalanga syndrome is a condition that was described in Uganda and various other African countries decades ago. Its features include …
Article scientifique
Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis)
The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a …
Article scientifique
Lentiviral vectors can be used for full-length dystrophin gene therapy
Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene therapy …
Article scientifique
Identification and expression analysis of the apple (Malus × domestica) basic helix-loop-helix transcription factor family
Basic helix-loop-helix (bHLH) proteins, which are characterized by a conserved bHLH domain, comprise one of the largest families of transcription …
Article scientifique
Microbiome sharing between children, livestock and household surfaces in western Kenya
The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household …
Article scientifique
Recent advances in occupational and environmental health hazards of workers exposed to gasoline compounds
The impact of health and environmental hazards, associated with the constituents of gasoline, on occupationally exposed workers has been recorded …
Article scientifique
Whole genome scan reveals the genetic signature of African Ankole cattle breed and potential for higher quality beef
BACKGROUND: Africa is home to numerous cattle breeds whose diversity has been shaped by subtle combinations of human and natural …
Article scientifique
A plant pathology perspective of fungal genome sequencing
The majority of plant pathogens are fungi and many of these adversely affect food security. This mini-review aims to provide …
Article scientifique
Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1
BACKGROUND: Arsenic trioxide (ATO) is commonly used in the treatment of acute promyelocytic leukemia (APL), but does not benefit patients …
Article scientifique
Identification and antimicrobial resistance patterns of bacterial enteropathogens from children aged 0–59 months at the University Teaching Hospital, Lusaka, Zambia: a prospective cross sectional study
BACKGROUND: Bacterial diarrhoeal disease is among the most common causes of mortality and morbidity in children 0-59 months at the …
Article scientifique
Molecular responses of genetically modified maize to abiotic stresses as determined through proteomic and metabolomic analyses
Some genetically modified (GM) plants have transgenes that confer tolerance to abiotic stressors. Meanwhile, other transgenes may interact with abiotic …
Article scientifique
Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model
Although a correlation between polymorphisms of NOD-like receptor family-pyrin domain containing 3 (NLRP3) and predisposition to type 1 diabetes (T1D) …
Article scientifique
Clustering of 770,000 genomes reveals post-colonial population structure of North America
Despite strides in characterizing human history from genetic polymorphism data, progress in identifying genetic signatures of recent demography has been …
Article scientifique
Carbonyl Cyanide m-Chlorophenylhydrazine (CCCP) Reverses Resistance to Colistin, but Not to Carbapenems and Tigecycline in Multidrug-Resistant Enterobacteriaceae
Background: Carbapenems (CAR), colistin (CST), and tigecycline (TGC) alone or in combination therapy has become the last-resort antibiotics for treating …
Article scientifique
Transcriptome analysis reveals the complexity of alternative splicing regulation in the fungus Verticillium dahliae
BACKGROUND: Alternative splicing (AS) regulation is extensive and shapes the functional complexity of higher organisms. However, the contribution of alternative …
Article scientifique
Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors
Pseudomonas aeruginosa is a Gram negative pathogenic bacteria involved in many human infections including otitis, keratitis, pneumonia and diabetic foot …
Article scientifique
X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3
By moving essential body fluids and molecules, motile cilia and flagella govern respiratory mucociliary clearance, laterality determination and the transport …