7361
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Biologie synthétique
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Publications
7361 publication(s) trouvée(s)
Article scientifique
Synthetic redesign of Escherichia coli for cadaverine production from galactose
With increasing concerns over the environment, biological production of cadaverine has been suggested as an alternative route to replace polyamides …
Article scientifique
Clinical Characteristics of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in Addis Ababa, Ethiopia: A Cross-Sectional Study
BACKGROUND: Diabetic ketoacidosis (DKA) is one of the most serious acute complications of type 1 diabetes (T1D) and the leading …
Article scientifique
Genome-wide identification, evolution and expression analysis of RING finger protein genes in Brassica rapa
More and more RING finger genes were found to be implicated in various important biological processes. In the present study, …
Article scientifique
Metabolomic Profiling in Individuals with a Failing Kidney Allograft
BACKGROUND: Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. METHODS: To explore metabolomic …
Article scientifique
Targeting pathogen metabolism without collateral damage to the host
The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or parasites) without causing collateral damage to healthy …
Article scientifique
The prevalence and factors associated with malnutrition among infants with cleft palate and/or lip at a hospital in Uganda: a cross-sectional study
BACKGROUND: To determine the prevalence and factors associated with malnutrition among infants with Cleft palate and/or cleft lip (CP+/-L) at …
Article scientifique
Effect of ginseng extract on the TGF-β1 signaling pathway in CCl4-induced liver fibrosis in rats
Liver diseases are major global health problems. Ginseng extract has antioxidant, immune-modulatory and anti-inflammatory activities. This study investigated the effect …
Article scientifique
First report on molecular breast cancer subtypes and their clinico-pathological characteristics in Eastern Morocco: series of 2260 cases
BACKGROUND: Breast cancer is the most frequent malignancy among women in Eastern Morocco. In this paper, we provide the first …
Article scientifique
Overexpression of PaNAC03, a stress induced NAC gene family transcription factor in Norway spruce leads to reduced flavonol biosynthesis and aberrant embryo development
BACKGROUND: The NAC family of transcription factors is one of the largest gene families of transcription factors in plants and …
Article scientifique
Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia
Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance …
Article scientifique
The extracellular proteome of two Bifidobacterium species reveals different adaptation strategies to low iron conditions
BACKGROUND: Bifidobacteria are among the first anaerobic bacteria colonizing the gut. Bifidobacteria require iron for growth and their iron-sequestration mechanisms …
Article scientifique
Lipidome determinants of maximal lifespan in mammals
Maximal lifespan of mammalian species, even if closely related, may differ more than 10-fold, however the nature of the mechanisms …
Article scientifique
The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor
β-TrCP and SKP2 are two well-studied F-box proteins, which often act as oncogenes. Whether and how they communicate with each …
Article scientifique
Improving the Conservation of Mediterranean Chondrichthyans: The ELASMOMED DNA Barcode Reference Library
Cartilaginous fish are particularly vulnerable to anthropogenic stressors and environmental change because of their K-selected reproductive strategy. Accurate data from …
Article scientifique
A review of therapeutic potentials of sweet potato: Pharmacological activities and influence of the cultivar
Sweet potato (Ipomoea batatas) is a global food crop, now being recognized as a functional food due to several of …
Article scientifique
Occurrence of Escherichia coli O157:H7 in cattle feces and contamination of carcass and various contact surfaces in abattoir and butcher shops of Hawassa, Ethiopia
BACKGROUND: Despite of the sanitation measures in municipal abattoirs to reduce contamination, Escherichia coli continues to be a health hazard. …
Article scientifique
Upregulated long non-coding RNA LINC00152 expression is associated with progression and poor prognosis of tongue squamous cell carcinoma
Altered expression of long non-coding RNAs (lncRNAs) associated with human carcinogenesis and might be used as diagnosis and prognosis biomarkers. …
Article scientifique
Completion of the Chloroplast Genomes of Five Chinese Juglans and Their Contribution to Chloroplast Phylogeny
Juglans L. (walnuts and butternuts) is an economically and ecologically important genus in the family Juglandaceae. All Juglans are important …
Article scientifique
Some current applications, limitations and future perspectives of lactic acid bacteria as probiotics
Several mechanism and non-mechanism-based studies supporting the claim that lactic acid bacteria (LAB) strains confer health benefits and play immune-modulatory …
Article scientifique
Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects
BACKGROUND: The CRISPR-Cas9 system is a widely utilized platform for transgenic animal production in various species, although its off-target effects …