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Publications
7361 publication(s) trouvée(s)
Article scientifique
E-cadherin genetic variants predict survival outcome in breast cancer patients
BACKGROUND: E-cadherin is a major component of adherens junctions that regulates cell shape and maintains tissue integrity. A complete loss …
Article scientifique
Alternative pre-approved and novel therapies for the treatment of anthrax
BACKGROUND: Bacillus anthracis, the causative agent of anthrax, is a spore forming and toxin producing rod-shaped bacterium that is classified …
Article scientifique
Radiation Damage in XFEL: Case study from the oxygen-evolving complex of Photosystem II
Abstract Structural changes induced by radiation damage in X-ray crystallography hinder the ability to understand the structure/function relationship in chemical …
Article scientifique
Comparative genomic analysis of the flagellin glycosylation island of the Gram-positive thermophile Geobacillus
BACKGROUND: Protein glycosylation involves the post-translational attachment of sugar chains to target proteins and has been observed in all three …
Article scientifique
Antifungal Streptomyces spp. Associated with the Infructescences of Protea spp. in South Africa
Common saprophytic fungi are seldom present in Protea infructescences, which is strange given the abundance of mainly dead plant tissue …
Article scientifique
The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold
Activation of Toll-like receptors induces dimerization and the recruitment of the death domain (DD) adaptor protein MyD88 into an oligomeric …
Article scientifique
Identifying mutations in Tunisian families with retinal dystrophy
Retinal dystrophies (RD) are a rare genetic disorder with high genetic heterogeneity. This study aimed at identifying disease-causing variants in …
Article scientifique
Computational Identification of Tissue-Specific Splicing Regulatory Elements in Human Genes from RNA-Seq Data
Alternative splicing is a vital process for regulating gene expression and promoting proteomic diversity. It plays a key role in …
Article scientifique
High Prevalence of Gut Microbiota Colonization with Broad-Spectrum Cephalosporin Resistant Enterobacteriaceae in a Tunisian Intensive Care Unit
Healthcare-associated infections due to cefotaxime-resistant Enterobacteriaceae (CRE) have become a major public health threat, especially in intensive care units (ICUs). …
Article scientifique
Mycosarcoma (Ustilaginaceae), a resurrected generic name for corn smut (Ustilago maydis) and its close relatives with hypertrophied, tubular sori
Ustilago is a polyphyletic genus of smut fungi found mainly on Poaceae . The development of a taxonomy that reflects …
Article scientifique
Effect of ozone gas processing on physical and chemical properties of wheat proteins
Purpose: To investigate the effects of ozone treatment on chemical and physical properties of wheat (Triticum aestivum L.) gluten, glutenin …
Article scientifique
Siropins, novel serine protease inhibitors from gut microbiota acting on human proteases involved in inflammatory bowel diseases
In eukaryotes, the serpins constitute a wide family of protease inhibitors regulating many physiological pathways. Many reports stressed the key …
Article scientifique
Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesis
BACKGROUND: The Cancer Atlas project has shown that p53 is the only commonly (96 %) mutated gene found in high-grade …
Article scientifique
Enterohemorrhagic Escherichia coli O157 in milk and dairy products from Libya: Isolation and molecular identification by partial sequencing of 16S rDNA
Aim: The aim of this work was to isolate and molecularly identify enterohemorrhagic Escherichia coli (EHEC) O157 in milk and …
Article scientifique
Determination of virulence and antibiotic resistance pattern of biofilm producing Listeria species isolated from retail raw milk
BACKGROUND: One of the foodborne pathogens is Listeria monocytogenes, which causes serious invasive illness in elderly and immunocompromised patients, pregnant …
Article scientifique
Cholera in Cameroon, 2000-2012: Spatial and Temporal Analysis at the Operational (Health District) and Sub Climate Levels
INTRODUCTION: Recurrent cholera outbreaks have been reported in Cameroon since 1971. However, case fatality ratios remain high, and we do …
Article scientifique
Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development
The relevance of specific microbial colonisation to colorectal cancer (CRC) disease pathogenesis is increasingly recognised, but our understanding of possible …
Article scientifique
Insight into the genetic composition of South African Sanga cattle using SNP data from cattle breeds worldwide
BACKGROUND: Understanding the history of cattle breeds is important because it provides the basis for developing appropriate selection and breed …
Article scientifique
Extended-Spectrum beta (β)-Lactamases and Antibiogram in Enterobacteriaceae from Clinical and Drinking Water Sources from Bahir Dar City, Ethiopia
BACKGROUND: The spread of Extended-Spectrum beta (β)-Lactamases (ESBL)-producing Enterobacteriaceae has become a serious global problem. ESBL-producing Enterobacteriaceae vary based on …
Article scientifique
PRIMO: An Interactive Homology Modeling Pipeline
The development of automated servers to predict the three-dimensional structure of proteins has seen much progress over the years. These …