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Publications
7361 publication(s) trouvée(s)
Article scientifique
The Limonoids TS3 and Rubescin E Induce Apoptosis in Human Hepatoma Cell Lines and Interfere with NF-κB Signaling
Hepatocellular carcinoma (HCC) is extremely resistant towards pharmacological therapy. To date, the multi-kinase inhibitor Sorafenib is the only available therapeutic …
Article scientifique
Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis
BACKGROUND: Rapid molecular diagnostics, with their ability to quickly identify genetic mutations associated with drug resistance in Mycobacterium tuberculosis clinical …
Article scientifique
Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells
Ethyl pyruvate, a known ROS scavenger and anti-inflammatory drug was found to combat leukemia cells. Tumor cell killing was achieved …
Article scientifique
An outbreak of Serratia liquefaciens at a rural health center in The Gambia
INTRODUCTION: Healthcare-associated infections (HAIs) are better documented in developed than in developing countries. There are emerging reports regarding the high …
Article scientifique
Molecular Cloning and Functional Expression of a Δ9- Fatty Acid Desaturase from an Antarctic Pseudomonas sp. A3
Fatty acid desaturase enzymes play an essential role in the synthesis of unsaturated fatty acids. Pseudomonas sp. A3 was found …
Article scientifique
Endosome-mediated endocytic mechanism replenishes the majority of synaptic vesicles at mature CNS synapses in an activity-dependent manner
Whether synaptic vesicles (SVs) are recovered via endosome-mediated pathways is a matter of debate; however, recent evidence suggests that clathrin-independent …
Article scientifique
Additive Effects of Millimeter Waves and 2-Deoxyglucose Co-Exposure on the Human Keratinocyte Transcriptome
Millimeter Waves (MMW) will be used in the next-generation of high-speed wireless technologies, especially in future Ultra-Broadband small cells in …
Article scientifique
Modestobacter lacusdianchii sp. nov., a Phosphate-Solubilizing Actinobacterium with Ability to Promote Microcystis Growth
A novel actinobacterium, designated strain JXJ CY 19T, was isolated from a culture mat of Microcystis aeruginosa FACHB-905 collected from …
Article scientifique
Comparison of pre-processing methods for multiplex bead-based immunoassays
BACKGROUND: High throughput protein expression studies can be performed using bead-based protein immunoassays, such as the Luminex® xMAP® technology. Technical …
Article scientifique
The Invalidation of HspB1 Gene in Mouse Alters the Ultrastructural Phenotype of Muscles
Even though abundance of Hsp27 is the highest in skeletal muscle, the relationships between the expression of HspB1 (encoding Hsp27) …
Article scientifique
A Family of CSαβ Defensins and Defensin-Like Peptides from the Migratory Locust, Locusta migratoria, and Their Expression Dynamics during Mycosis and Nosemosis
Insect defensins are effector components of the innate defense system. During infection, these peptides may play a role in the …
Article scientifique
Seabird acoustic communication at sea: a new perspective using bio-logging devices
Most seabirds are very noisy at their breeding colonies, when aggregated in high densities. Calls are used for individual recognition …
Article scientifique
QTL Mapping in Three Rice Populations Uncovers Major Genomic Regions Associated with African Rice Gall Midge Resistance
African rice gall midge (AfRGM) is one of the most destructive pests of irrigated and lowland African ecologies. This study …
Article scientifique
Role of nanotechnology and gene delivery systems in TRAIL based therapies
Since its identification as a member of the tumour necrosis factor (TNF) family, TRAIL (TNF-related apoptosis-inducing ligand) has emerged as …
Article scientifique
Unique Clones of Vibrio cholerae O1 El Tor with Haitian Type ctxB Allele Implicated in the Recent Cholera Epidemics from Nigeria, Africa
BACKGROUND AND OBJECTIVES: The antimicrobial susceptibility patterns and genetic characteristics of Vibrio cholerae O1, which is responsible for several cholera …
Article scientifique
CpG site methylation in CRYAA promoter affect transcription factor Sp1 binding in human lens epithelial cells
BACKGROUND: Age-related cataract (ARC) is the leading cause of visual impairment worldwide, and α-crystallin (CRYAA) is the predominant structural protein …
Article scientifique
Characteristics of ciprofloxacin-resistant Enterobacteriaceae isolates recovered from wastewater of an Algerian hospital
INTRODUCTION: Hospital effluents are a source of environmental pollution by drugs, antibiotic-resistant bacteria, and resistance genes. Quinolones, particularly ciprofloxacin, are …
Article scientifique
Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases
We performed a Phenome-Wide Association Study (PheWAS) to identify interrelationships between the immune system genetic architecture and a wide array …
Article scientifique
Novel pH-Sensitive Cyclic Peptides
A series of cyclic peptides containing a number of tryptophan (W) and glutamic acid (E) residues were synthesized and evaluated …
Article scientifique
eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants
BACKGROUND: We explored premature stop-gain variants to test the hypothesis that variants, which are likely to have a consequence on …