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Publications
7361 publication(s) trouvée(s)
Article scientifique
Development of a prospective cohort of HIV Exposed Sero-Negative (HESN) individuals in Jos Nigeria
BACKGROUND: HIV/AIDS continues to be a global health problem. With currently no cure, it is critical to get an effective …
Article scientifique
Anti-cancer and antioxidant properties of phenolics isolated from Toona sinensis A Juss acetone leaf extract
Purpose: To investigate the antioxidant and anticancer activities of phenolics from the leaf extract of Toona sinensis (TS).Methods: Acetone leaf …
Article scientifique
Spatial and Temporal Variation in Selection of Genes Associated with Pearl Millet Varietal Quantitative Traits In situ
Ongoing global climate changes imply new challenges for agriculture. Whether plants and crops can adapt to such rapid changes is …
Article scientifique
Transgenic Mouse Expressing Optical MicroRNA Reporter for Monitoring MicroRNA-124 Action during Development
MicroRNAs (miRNAs) fine-tune target protein synthesis by suppressing gene expression, temporally changing along development and possibly in pathological conditions. A …
Article scientifique
Boronic acid disk diffusion for the phenotypic detection of polymerase chain reaction-confirmed, carbapenem-resistant, gram-negative bacilli isolates
BACKGROUND: The Middle East is regarded as a secondary reservoir for OXA-48 and New Delhi metallo-β-lactamase (NDM) carbapenemases. One of …
Article scientifique
FastRNABindR: Fast and Accurate Prediction of Protein-RNA Interface Residues
A wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and assembly of many viruses …
Article scientifique
Case report of Lewy body disease mimicking Creutzfeldt-Jakob disease in a 44-year-old man
BACKGROUND: Few patients are reported with dementia with Lewy bodies before fifty years-old, which may partly reflect the difficulty of …
Article scientifique
In vivo and in vitro inhibition of rat liver glutathione transferases activity by extracts from Combretum zeyheri (Combretaceae) and Parinari curatellifolia (Chrysobalanaceae)
BACKGROUND: Parinari curatellifolia and Combretum zeyheri are medicinal plants used in Zimbabwe and other Southern African countries for stomach ailments, …
Article scientifique
Exome sequencing discloses KALRN homozygous variant as likely cause of intellectual disability and short stature in a consanguineous pedigree
BACKGROUND: The recent availability of whole-exome sequencing has opened new possibilities for the evaluation of individuals with genetically undiagnosed intellectual …
Article scientifique
COMODI: an ontology to characterise differences in versions of computational models in biology
BACKGROUND: Open model repositories provide ready-to-reuse computational models of biological systems. Models within those repositories evolve over time, leading to …
Article scientifique
Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3
Rabies is a neglected zoonotic disease that has no effective treatment after onset of illness. However the disease can be …
Article scientifique
Multivariate characterization of morphological traits in West African cattle sires
Abstract. A total of 183 adult sires belonging to nine West African cattle breeds sampled in 67 villages of Mali, …
Article scientifique
Genotype-phenotype analysis of von Hippel-Lindau syndrome in Korean families: HIF-α binding site missense mutations elevate age-specific risk for CNS hemangioblastoma
BACKGROUND: von Hippel-Lindau (VHL) disease is a rare hereditary tumor syndrome caused by VHL gene mutations that is characterized by …
Article scientifique
Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma
BACKGROUND: The mitochondrial GTPase mitofusin-2 (MFN2) gene encodes a mitochondrial membrane protein that can induce apoptosis of hepatocellular carcinoma (HCC) …
Article scientifique
Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury
BACKGROUND: It is well established that some irradiated liver non-parenchymal cells secrete pro-inflammatory cytokines to facilitate the development of radiation-induced …
Article scientifique
Allovahlkampfia spelaea Causing Keratitis in Humans
BACKGROUND: Free-living amoebae are present worldwide. They can survive in different environment causing human diseases in some instances. Acanthamoeba sp. …
Article scientifique
Effect of Cryopreservation and Post-Cryopreservation Somatic Embryogenesis on the Epigenetic Fidelity of Cocoa (Theobroma cacao L.)
UNLABELLED: While cocoa plants regenerated from cryopreserved somatic embryos can demonstrate high levels of phenotypic variability, little is known about …
Article scientifique
Expression patterns, mutation detection and RNA interference of Rhopalosiphum padi voltage-gated sodium channel genes
The voltage-gated sodium channel (VGSC) is the target of sodium-channel-blocking insecticides. Traditionally, animals were thought to have only one VGSC …
Article scientifique
Prevalence of pathogenic free-living amoeba and other protozoa in natural and communal piped tap water from Queen Elizabeth protected area, Uganda
BACKGROUND: Pathogenic water dwelling protozoa such as Acanthamoeba spp., Hartmannella spp., Naegleria spp., Cryptosporidium spp. and Giardia spp. are often …
Article scientifique
Structural and Catalytic Characterization of a Fungal Baeyer-Villiger Monooxygenase
Baeyer-Villiger monooxygenases (BVMOs) are biocatalysts that convert ketones to esters. Due to their high regio-, stereo- and enantioselectivity and ability …