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7361 publication(s) trouvée(s)
Article scientifique
Polymorphisms of Estrogen Metabolism-Related Genes and Prostate Cancer Risk in Two Populations of African Ancestry
BACKGROUND: Estrogens are thought to play a critical role in prostate carcinogenesis. It has been suggested that polymorphisms of genes …
Article scientifique
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined
Over the past two decades, huge amounts of research were launched to understand the functions of sphingosine. Many pathways were …
Article scientifique
Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications
MicroRNAs (miRNAs) represent a class of small non-coding RNA (sncRNA) molecules that can regulate mRNAs by inducing their degradation or …
Article scientifique
Structured feature selection using coordinate descent optimization
BACKGROUND: Existing feature selection methods typically do not consider prior knowledge in the form of structural relationships among features. In …
Article scientifique
Association of MicroRNA-196a2 Variant with Response to Short-Acting β2-Agonist in COPD: An Egyptian Pilot Study
Chronic obstructive pulmonary disease (COPD) is a multifactorial chronic respiratory disease, characterized by an obstructive pattern. Understanding the genetic predisposition …
Article scientifique
Overconfidence, Incentives and Digit Ratio
This paper contributes to a better understanding of the biological underpinnings of overconfidence by analyzing performance predictions in the Cognitive …
Article scientifique
Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium
BACKGROUND: The search for new antimalarial drugs has become increasingly urgent due to plasmodial resistance to existing drugs. As part …
Article scientifique
Fluoroquinolone-Resistant Enteric Bacteria in Sub-Saharan Africa: Clones, Implications and Research Needs
Fluoroquinolones came into widespread use in African countries in the early 2000s, after patents for the first generation of these …
Article scientifique
Infections caused by extended-spectrum beta-lactamases producing Enterobacteriaceae: clinical and economic impact in patients hospitalized in 2 teaching hospitals in Dakar, Senegal
BACKGROUND: Infections caused by extended-spectrum beta-lactamases producing Enterobacteriaceae (ESBL-E) are of major concern in clinical practice because of limited therapeutic …
Article scientifique
Dynamics of the Developing Chick Chorioallantoic Membrane Assessed by Stereology, Allometry, Immunohistochemistry and Molecular Analysis
The chick chorioallantoic membrane (CAM) is a widely used model for the study of angiogenesis, tumour growth, as well as …
Article scientifique
MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity
BACKGROUND: Disturbance of the equilibrium between reactive oxygen species (ROS) and anti-oxidants (AOX) has been implicated in various diseases, including …
Article scientifique
Metagenomic Analysis of Antibiotic-Induced Changes in Gut Microbiota in a Pregnant Rat Model
Food and Drug Administration (FDA, USA)-approved category B antibiotics are commonly prescribed to treat infections during pregnancy. The aim of …
Article scientifique
Predictors of blaCTX-M-15 in varieties of Escherichia coli genotypes from humans in community settings in Mwanza, Tanzania
BACKGROUND: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae commonly cause infections worldwide. Bla CTX-M-15 has been commonly detected in hospital isolates in Mwanza, …
Article scientifique
A Carotenoid-Deficient Mutant in Pantoea sp. YR343, a Bacteria Isolated from the Rhizosphere of Populus deltoides, Is Defective in Root Colonization
The complex interactions between plants and their microbiome can have a profound effect on the health and productivity of the …
Article scientifique
Antimicrobial susceptibility profiles of Escherichia coli and Klebsiella pneumoniae isolated from outpatients in urban and rural districts of Uganda
BACKGROUND: Antimicrobial resistance is a global public health concern contributing to increased morbidity and mortality particularly in low-income countries. Studies …
Article scientifique
High prevalence of multidrug resistant Enterobacteriaceae isolated from outpatient urine samples but not the hospital environment in Bo, Sierra Leone
BACKGROUND: The rising level of antimicrobial resistance among bacterial pathogens is one of the most significant public health problems globally. …
Article scientifique
Comparison of Clinical Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing guidelines for the interpretation of antibiotic susceptibility at a University teaching hospital in Nairobi, Kenya: a cross-sectional study
BACKGROUND: The Clinical Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines are the most …
Article scientifique
The Gonium pectorale genome demonstrates co-option of cell cycle regulation during the evolution of multicellularity
The transition to multicellularity has occurred numerous times in all domains of life, yet its initial steps are poorly understood. …
Article scientifique
Comparative analysis of ear-hole closure identifies epimorphic regeneration as a discrete trait in mammals
Why mammals have poor regenerative ability has remained a long-standing question in biology. In regenerating vertebrates, injury can induce a …
Article scientifique
Species boundaries in plant pathogenic fungi: a Colletotrichum case study
BACKGROUND: Accurate delimitation of plant pathogenic fungi is critical for the establishment of quarantine regulations, screening for genetic resistance to …