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Biologie synthétique
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Publications
7377 publication(s) trouvée(s)
Article scientifique
Two lives, one bite: a six-year retrospective study on snakebite envenoming among pregnant women in Northeastern Nigeria
Introduction Pregnant women with neglected tropical diseases like snakebites are considered doubly neglected due to the intersection of multiple vulnerabilities, …
Article scientifique
The involvement of exosomes in the tumorigenicity of breast cancer cell lines through the crosstalk between STAT3, Notch, and Wnt signaling pathways
BACKGROUND: Exosomes play a critical role in the tumor microenvironment by interacting with signaling pathways that facilitate breast cancer metastasis, …
Article scientifique
Plasmodium telomere maintenance: uncovering the Achilles’ heel for novel antimalarials
This review examines the potential of disrupting telomere maintenance in Plasmodium as a novel antimalarial strategy. Telomeres are repetitive DNA–protein …
Article scientifique
Expression profiling of KRAS and NOXA genes as prospective biomarkers in ovarian carcinoma
BACKGROUND: Ovarian cancer (OC) is a leading cause of cancer deaths in women. Comprehensive molecular studies are required to understand …
Article scientifique
SNP markers revealed the genetic diversity and population structure of Mesosphaerum suaveolens (L.) Kuntze Syn. Hyptis suaveolens (L.) Poit accessions collected in Benin
Mesosphaerum suaveolens (L.) Kuntze is a wild species with many biological activities in medicine. The species can potentially serve as …
Article scientifique
Comparative application of machine learning approaches for body weight prediction in non-descript indigenous goats at different growth stages
Background and Aim: Accurate prediction of body weight (BW) in goats is vital for breeding, feeding, drug administration, and marketing …
Article scientifique
In vitro activity of meropenem-vaborbactam combinations and eravacycline against carbapenem-resistant Acinetobacter baumannii
Abstract Treatment of carbapenem-resistant Acinetobacter baumannii (CRAB) presents a growing clinical challenge. This study evaluated the in vitro efficacy of …
Article scientifique
Optimization of absorption coefficient of quantum dot structures for infrared spectroscopy
Abstract Infrared spectroscopy is a powerful tool used in chemical analysis and identification, material and polymer characteristics, pharmaceuticals and medical …
Article scientifique
SDC2 and FN as cargo proteins in circulating extracellular vesicles in obese breast cancer patients with lymph node metastasis
Lymph node metastasis (LNM) is a pivotal determinant of breast cancer (BC) patient prognosis and treatment efficacy. Cell surface heparan …
Article scientifique
One health approach unravels worrying antimicrobial resistance patterns: A cross-sectional study in Kisii, Kenya
BACKGROUND: Antimicrobial resistance (AMR) is a major public health challenge, particularly in Sub-Saharan Africa, where diagnostic and surveillance capacities are …
Article scientifique
The gut and lung microbiome across the TB disease spectrum
, progression to TB, response to antimycobacterial chemotherapy, and the propensity to develop post-infectious sequelae have all been linked to …
Article scientifique
Anti-inflammatory and cytotoxic assessment of flavonoids isolated from Viola odorata flowers with computer-guided docking study
The therapeutic potential of plant-derived polyphenols has garnered significant attention due to their roles in modulating inflammation and cancer progression. …
Article scientifique
Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1
Metabolic syndrome (MetS) is a widespread, complex health issue that poses a substantial global health burden with increased healthcare costs …
Article scientifique
Marine-derived peptides from Rapana venosa inhibit breast cancer cell growth through synergistic mechanisms with doxorubicin
Abstract Marine natural products are a promising source of novel anticancer agents. This study evaluated the antitumor activity of peptide …
Article scientifique
Coexistence of carbapenem resistance and hypervirulence in clinical Klebsiella pneumoniae isolates: a molecular and phenotypic analysis
Abstract Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CRhvKp) is increasingly recognized as the predominant nosocomial pathogen in healthcare environments. Objective This …
Article scientifique
A review on knowledge and information extraction from PDF documents and storage approaches
Introduction: Automating the extraction of information from Portable Document Format (PDF) documents represents a major advancement in information extraction, with …
Article scientifique
Unravelling novel microbial players in the breast tissue of TNBC patients: a meta-analytic perspective
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC), accounting for nearly 40% of BC-related deaths. …
Article scientifique
Direct-acting antiviral treatment significantly shaped the gut microbiota in chronic hepatitis C patients: a pilot study
Background Chronic hepatitis C (CHC) can be effectively cured with direct-acting antivirals (DAAs), yet the impact of CHC on the …
Article scientifique
Optimization of protease production by newly isolated Bacillus sp. from the Red Sea using defatted soybean cake
In this study, three strains of alkaline protease-producing bacteria were isolated from marine seawater collected at a depth of 15 …
Article scientifique
Design, synthesis, and biological assessment of a novel series of coumarin-tethered thiazole derivatives as potential antibacterial agents
Since the discovery of penicillin in the 1930s, antibiotics have been the primary treatment for bacterial infections. However, antimicrobial resistance …