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7377 publication(s) trouvée(s)
Article scientifique
A novel sulfamoylphenyl-dihydro-thiadiazole derivative as a dual EGFR and carbonic anhydrase inhibitor for cancer therapy
A novel sulfamoylphenyl-dihydro-thiadiazole derivative (compound 14) has been designed and synthesized as a dual inhibitor targeting EGFR and human carbonic …
Article scientifique
Wild birds as potential reservoirs of antimicrobial-resistant Escherichia coli: a systematic review
Antimicrobial resistance (AMR) is currently a major global problem affecting humans, animals, and the environment. The role of wild birds …
Article scientifique
Risk factors associated with rectal carriage of carbapenem resistant Enterobactorales in northern Nigeria: A hospital surveillance
Article scientifique
Behavioural alterations and cerebellar toxicity induced by Datura metel exposure in mice
Purpose: To investigate the neurotoxic effects of methanolic crude extract of leaves of Datura metel L. Solanaceae on the cerebellum …
Article scientifique
Evaluation of ssDNA aptamer binding to Aurora Kinase A and its cytotoxic effects on HeLa and MCF-7 cancer cell lines
Purpose: To investigate the binding potential of ssDNA aptamer to Aurora kinase A (AURKA) and assess its inhibitory effect on …
Article scientifique
Study of two lactases for the manufacture of lactose-free yogurt by K-Lolac enzymatic method
Purpose: To investigate the efficiency of two lactase enzymes in producing lactose-free yogurt. Methods: Two lactase enzymes (NOLA™5500 fit and …
Article scientifique
Artificial Intelligence for Genomics and Bioinformatics: Is Africa Lagging Behind?
Summary Africa’s diverse pathogen and human genetics present significant opportunities for genomic medicine research using artificial intelligence (AI). We surveyed …
Article scientifique
Targeting Age-Associated NAD⁺ Decline: in silico Evaluation of Minocycline as an Inhibitor of CD38 and PARP2
Article scientifique
Methyl jasmonate and salicylic acid synergism enhances phloroglucinol content in shoot cultures of Astragalus fruticosus Forssk
Introduction Astragalus fruticosus Forssk. is a plant species with potential for producing valuable secondary metabolites, such as phloroglucinol, which has …
Article scientifique
Randomised Complete Block Design on Biyinzika Dairy Meal Supplementation and Physicochemical Properties of Milk Quality in Uganda’s South-Western Cattle Corridor
Article scientifique
Minocycline Extends Lifespan through Boosting NAD + levels, Reducing Inflammation, and Regulating Gut Microbiome Dynamics in Drosophila melanogaster
Article scientifique
Examining epidemiological models and economic analyses of Typhoid Conjugate Vaccine: A scoping review
Abstract Typhoid remains a preventable disease that primarily affects low- and middle-income countries. We conducted a scoping review to synthesize …
Article scientifique
Case Report: Deficiency in Adenosine Deaminase 2 mimicking a childhood Polyarteritis Nodosa: A case report of two siblings with a novel mutation
Background Polyarteritis Nodosa (PAN) is a systemic vasculitis with cutaneous, renal, cerebral and arterial manifestations. At an early age, it …
Article scientifique
Characterization of a novel polyfunctional “metalloglyco-protein/polypeptide-organochlorine” bioflocculant containing saturated nitro compounds, sulfones, polysulfides, phosphorus chlorine compounds, magnesium oxide, and metal chlorides, produced from Pseudomonas aeruginosa strain F29, isolated from porcine faeces in Nigeria
Article scientifique
Computational Design and Evaluation of N-Aryl Oxamic Acid Derivatives Targeting Mycobacterium Tuberculosis Protein Tyrosine Phosphatase B (PtpB): 2D-QSAR, Molecular docking, MD Simulations, DFT, and Pharmacokinetic Profiling
Article scientifique
Making MALDI-TOF MS for entomological parameters accessible: A practical guide for in-house library creation
Matrix-assisted laser desorption-ionisation time of flight mass spectrometry (MALDI-TOF MS) is a powerful analytical method that has been used extensively …
Article scientifique
Physiological, molecular and histological response of Pentodon bispinosus larvae (Coleoptera: Scarabaeidae) as a novel bioindicator for soil pollutants
This study investigates the impact of soil pollution exposure on the physiological and cellular homeostasis of Pentodon bispinosus larvae. The …
Article scientifique
Surgical Procedure Recognition Using Quantum Machine Learning
Abstract Surgical procedure recognition is the process of identifying tasks and gestures done during a surgical process and is a …
Article scientifique
Expression of Long Non-Coding RNA-NEAT-1 in Papillary Thyroid Carcinoma in Relation to Immunohistochemical expression of CD8 and PD-L1 as Indicators of Tumor Immune Microenvironment
OBJECTIVE: Investigation of CD8 and PD-L1 immunohistochemical expression, as indicators of tumor microenvironment in PTC, and their correlation with lncRNA-NEAT1 …
Article scientifique
Management Outcome of Diabetic Keto Acidosis and Associated Factors among Adult Patients Admitted in the Emergency room of ST. Peter Specialized Hospital, Addis Ababa, Ethiopia, 2022