7359
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38559
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Biologie synthétique
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Publications
7359 publication(s) trouvée(s)
Article scientifique
An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial—an update to the published protocol
This article reports an update to the protocol of the IMASOY trial, which was prospectively registered on clinicaltrials.gov (NCT04110340) in …
Article scientifique
RNA Interference based Midkine Gene Therapy for Hepatocellular Carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) arises from hepatocytes and accounts for 90% of primary liver cancer. Reasons for HCC prognosis remaining …
Article scientifique
Uptake of protective tetanus toxoid vaccine doses and maternal associated factors during pregnancy in armed conflict zone, hospital-based cross-sectional study
Background Vaccinating pregnant women with tetanus toxoid (TT) is crucial to prevent neonatal tetanus, reducing related deaths by 94%. In …
Article scientifique
Whole-genome sequencing of multidrug-resistant Escherichia coli causing urinary tract infection in an immunocompromised patient: a case report
Abstract Background Escherichia coli is a major human pathogen responsible for a broad range of clinical illnesses. It has been …
Article scientifique
Metformin in Combination with Standard Therapy in Patients with Diffuse Large B-Cell Lymphoma: A Randomized Phase II Clinical Trial
BACKGROUND: Metformin has been shown to have antitumor activity in different tumor types. In DLBCL (Diffuse large B cell lymphoma), …
Article scientifique
miRNAs: possible regulators of toll like receptors and inflammatory tumor microenvironment in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is ranked as the third most commonly diagnosed cancer and the third cause of cancer related …
Article scientifique
Comparable to 17α- methyl testosterone, dietary supplements of Tribulus terrestris and Mucuna pruriens promote the development of mono-sex, all-male tilapia fry, growth, survival rate and sex-related genes (Amh, Sox9, Foxl2, Dmrt1)
To evaluate Tribulus terrestris and Mucuna pruriens for inducing all-male tilapia, mixed-sex Nile tilapia, Oreochromis niloticus, (mean weight 0.025 ± …
Article scientifique
Cost of Cholera for Households and Health Facilities, Somalia
INTRODUCTION: Cholera remains a substantial public health challenge in Somalia. Ongoing droughts in the country have caused significant outbreaks which …
Article scientifique
Elucidating the biotechnological potential of the genera Parageobacillus and Saccharococcus through comparative genomic and pan-genome analysis
BACKGROUND: The genus Geobacillus and its associated taxa have been the focal point of numerous thermophilic biotechnological investigations, both at …
Article scientifique
Insights into the genomic homogeneity of Moroccan indigenous sheep breeds though the lens of runs of homozygosity
Numerous studies have indicated that Morocco's indigenous sheep breeds are genetically homogenous, posing a risk to their survival in the …
Article scientifique
Colistin-, cefepime-, and levofloxacin-resistant Salmonella enterica serovars isolated from Egyptian chicken carcasses
Abstract Objectives The emergence of multidrug-resistant (MDR) Salmonella strains, especially resistant ones toward critically important antimicrobial classes such as fluoroquinolones …
Article scientifique
In silico exploration of anti-prostate cancer compounds from differential expressed genes
Abstract Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study …
Article scientifique
Investigating the footprint of post-domestication dispersal on the diversity of modern European, African and Asian goats
Abstract Background Goats were domesticated in the Fertile Crescent about 10,000 years before present (YBP) and subsequently spread across Eurasia …
Article scientifique
Genomic characterization of multi drug resistant ESBL-producing Escherichia coli isolates from patients and patient environments in a teaching hospital in Ghana
Abstract Background ESBL-producing Escherichia coli pose a growing health risk in community and healthcare settings. We investigated the resistome, virulome, …
Article scientifique
Revealing detrimental effects of various DC electrical energy conditions on different multidrug resistant bacteria: a comprehensive study
The arbitrary discharge of contaminated wastes, especially that encompass multidrug resistant microbes (MDR), would broaden the circle of epidemic diseases …
Article scientifique
Genetic engineering and genome editing technologies as catalyst for Africa’s food security: the case of plant biotechnology in Nigeria
Many African countries are unable to meet the food demands of their growing population and the situation is worsened by …
Article scientifique
Genomic insights into the 2022–2023Vibrio cholerae outbreak in Malawi
Abstract Malawi experienced its deadliest Vibrio cholerae ( Vc ) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths …
Article scientifique
Emerging biomarkers for non-invasive diagnosis and treatment of cancer: a systematic review
Cancer remains a global health challenge, necessitating continuous advancements in diagnostic and treatment strategies. This review focuses on the utility …
Article scientifique
In silico Prediction of Anti-bacterial Potentials of Some Synthesized Sulfonamide Compounds
Overuse and misuse of antibiotics as well as social and economic factors have accelerated the spread of antibiotic-resistant bacteria, making …
Article scientifique
Insilico Studies of activities of compounds from Ricinodendron heudelotii against inflammatory and oxidant enzymes Carbonic anhydrase
Medicinal plants have been acclaimed and documented over the years to play vital role in promoting human health. The study …