396 publication(s) trouvée(s)
Article scientifique
The urgent need for African research collaboration on medicine quality
Substandard and falsified medicines threaten African health systems, yet research on this crisis is fragmented and concentrated in few countries, …
Article scientifique
Individual and population-level risk factors for new HIV infections among adults in Eastern and Southern Africa
Despite substantial recent declines, general population HIV incidence in sub-Saharan Africa remains above international targets. Better description of risk factors …
Article scientifique
Multiple local PfDHFR I164L haplotype expansions drive Plasmodium falciparum antifolate resistance in Uganda
Mutations in the Plasmodium falciparum genes, pfdhfr and pfdhps, drive antifolate resistance and threaten malaria control in regions where sulfadoxine-pyrimethamine …
Article scientifique
System-wide investments generate health and enhance HIV, TB and malaria control in Malawi
Abstract Global health initiatives have expanded access to HIV, tuberculosis, and malaria services in low-income countries, yet these programmes often …
Article scientifique
Birth season shapes the infant metabolome and development in Tanzania: a secondary explorative analysis of the early life interventions for childhood growth and development in Tanzania (ELICIT) trial
Rural communities in resource-limited settings are exposed to seasonal patterns in food insecurity. The pre- and early post-natal period is …
Article scientifique
Impact and cost-effectiveness of the community-led AMETHIST intervention among female sex workers in Zimbabwe
Female sex workers (FSW) face high HIV risk of HIV transmission and acquisition. The AMETHIST ("Adapted Microplanning: Eliminating Transmissible HIV …
Article scientifique
Decline in HIV prevalence among female sex workers in Zimbabwe between 2013 and 2023
HIV epidemic trends among female sex workers in sub-Saharan Africa are rarely known. We analysed HIV prevalence trends among 10,562 …
Article scientifique
Onset of persistent surface ocean oxygenation during the Great Oxidation Event
Abstract Free oxygen (O 2 ) first began accumulating in Earth’s atmosphere shortly after the Archean-Proterozoic transition during the ‘Great …
Article scientifique
Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions
As insecticide resistance spreads in Africa, next-generation insecticide-treated nets (ITNs) are increasingly being deployed to protect vulnerable populations against malaria. …
Article scientifique
Iron absorption and loss, and efficacy of iron supplementation with and without prebiotics in children with virally suppressed HIV: three prospective studies in South Africa
Children living with HIV are at risk for iron deficiency, yet optimal strategies for prevention and treatment remain unclear. Here, …
Article scientifique
Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries
Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are …
Article scientifique
Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia
In resource-limited settings, children often experience poor growth following illness, but the mechanisms are poorly understood. This cohort study in …
Article scientifique
Pyrogenic carbon contribution to tropical savanna soil carbon storage
Abstract Savannas are fire-prone ecosystems that contribute substantially to global fire emissions, but these emissions may be partly offset by …
Article scientifique
Using metagenomics and whole-genome sequencing to characterize enteric pathogens across various sources in Africa
Foodborne diseases (FBDs) remain a major public health concern in low- and middle-income countries (LMICs), with the African region carrying …
Article scientifique
Circulation of Salmonella spp. between humans, animals and the environment in animal-owning households in Malawi
Diverse salmonellae have the potential to cause disease and may be carried asymptomatically within the intestine of many vertebrate species. …
Article scientifique
Early Oldowan technology thrived during Pliocene environmental change in the Turkana Basin, Kenya
Approximately 2.75 million years ago, the Turkana Basin in Kenya experienced environmental changes, including increased aridity and environmental variability. Namorotukunan …
Article scientifique
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes
Antimicrobial resistance genes (ARGs) have rapidly emerged and spread globally, but the pathways driving their spread remain poorly understood. We …
Article scientifique
Author Correction: Multiplex bead assays enable integrated serological surveillance and reveal cross-pathogen vulnerabilities in Zambezia Province, Mozambique
In the version of the article initially published, in the Fig. 4 colour bar header and in the first sentence …
Article scientifique
Estimating rates of treatment delay for malaria fevers among children in Sub-Saharan Africa 2006–2022
Late diagnosis and treatment of malaria increase the odds of severe disease by nearly 2.8 times, enhance transmission rates, compromise …
Article scientifique
Sensitive near point-of-care detection of asymptomatic and submicroscopic Plasmodium falciparum infections in African endemic countries
Limited diagnostic capacity for detecting asymptomatic malaria infections with low parasite densities hinders elimination efforts in Africa. Here, we adapt …