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Biologie synthétique
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Publications
7343 publication(s) trouvée(s)
Article scientifique
Spatial diarrheal disease risks and antibiogram diversity of diarrheagenic Escherichia coli in selected access points of the Buffalo River, South Africa
Freshwater sources, often used for domestic and agricultural purposes in low- and middle-income countries are repositories of clinically significant bacterial …
Article scientifique
Rhizopus stolonifer biomass catalytic transesterification capability: optimization of cultivation conditions
Abstract Background Using fungal biomass for biocatalysis is a potential solution for the expensive cost of the use o enzymes. …
Article scientifique
A case for routine microbial diagnostics: Results from antimicrobial susceptibility testing in post-traumatic wound infections at a Ugandan tertiary care hospital
The global spread of antimicrobial resistance (AMR) poses an increasing challenge for clinicians in Uganda, where microbiological diagnostics are not …
Article scientifique
Resource availability and capacity to implement multi-stranded cholera interventions in the north-east region of Nigeria
BACKGROUND: Limited healthcare facility (HCF) resources and capacity to implement multi-stranded cholera interventions (water, sanitation, and hygiene (WASH), surveillance, case …
Article scientifique
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78
BACKGROUND: Cells can die through a process called apoptosis in both pathological and healthy conditions. Cancer development and progression may …
Article scientifique
Feasibility of cancer genetic counselling and screening in Cameroon: perceived benefits and barriers
Because there was no genetic testing service in Cameroon, we assessed the acceptance, perceived benefits and barriers and willingness to …
Article scientifique
Understanding the underlying genetic mechanisms for age at first calving, inter-calving period and scrotal circumference in Bonsmara cattle
BACKGROUND: Reproduction is a key feature of the sustainability of a species and thus represents an important component in livestock …
Article scientifique
Efficacy of zinc oxide and copper oxide nanoparticles on virulence genes of avian pathogenic E. coli (APEC) in broilers
BACKGROUND: Colibacillosis is one of the broilers' most dominant bacterial diseases, either as a primary or a secondary infection. As …
Article scientifique
Rebound increase in microRNA levels at the end of 5-FU-based therapy in colorectal cancer patients
Treatment with 5-fluorouracil (5-FU) based therapy is still used for colorectal cancer (CRC). Epigenetics has become a focus of study …
Article scientifique
Production, statistical evaluation and characterization of chitosanase from Fusarium oxysporum D18
Abstract Purpose The present research work focuses on the extraction of chitosanase enzyme from soil fungi. Chitosan hydrolysis by chitosanase …
Article scientifique
Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors
Globally, colorectal cancer (CRC) is a major health concern. Despite improvements in CRC treatment, mortality rates remain high. Genetic instability …
Article scientifique
Use of the mCherry fluorescent protein to optimize the expression of class I lanthipeptides in Escherichia coli
BACKGROUND: Lanthipeptides are a rapidly expanding family of ribosomally synthesized and post-translationally modified natural compounds with diverse biological functions. Lanthipeptide …
Article scientifique
Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function
Despite recent efforts to increase diversity in genome-wide association studies (GWASs), most loci currently associated with kidney function are still …
Article scientifique
Molecular characterization of Carbapenem-resistant Escherichia coli isolates from sewage at Mulago National Referral Hospital, Kampala: a cross-sectional study
Abstract Background Escherichia coli (E. coli) is one of the most frequent causes of fatal bacterial infections affecting both humans …
Article scientifique
Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors
Non-communicable diseases (NCDs) are rising rapidly in urbanizing populations in sub-Saharan Africa. Assessment of inflammatory and metabolic characteristics of a …
Article scientifique
Incidence and predictors of mortality in children with diabetic ketoacidosis in the comprehensive specialized referral hospitals of West Amhara Region, Northwest Ethiopia: a retrospective follow-up study
Background: Diabetic ketoacidosis is one of the major life-threatening conditions associated with acute metabolic complications. It remains a major public …
Article scientifique
Listeria monocytogenes in ready to eat meat products from Zambia: phenotypical and genomic characterization of isolates
The contamination of ready to eat foods (RTE) products due to Listeria monocytogenes could compromise the products safety becoming a …
Article scientifique
In vitro evaluation of antagonistic potentiality of Trichoderma harzianum against Diplodia spp. phytopathogenics fungi
Abstract Background Trichoderma species are able to cause significant changes in the metabolism of host plants, by that means it …
Article scientifique
Prevalence of Listeria monocytogenes in milk in Africa: a generalized logistic mixed-effects and meta-regression modelling
Abstract Listeria outbreaks and food recalls is on the raise globally. Milk particularly is highly susceptible to Listeria as its …
Article scientifique
Delineating intra-tumoral heterogeneity and tumor evolution in breast cancer using precision-based approaches
The burden of breast cancer continues to increase worldwide as it remains the most diagnosed tumor in females and the …