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Biologie synthétique
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Publications
7343 publication(s) trouvée(s)
Article scientifique
The African Goat Improvement Network: a scientific group empowering smallholder farmers
The African Goat Improvement Network (AGIN) is a collaborative group of scientists focused on genetic improvement of goats in small …
Article scientifique
Expression status of circ-SMARCA5, circ-NOL10, circ-LDLRAD3, and circ-RHOT1 in patients with colorectal cancer
Colorectal cancer (CRC) poses a significant burden on both the healthcare systems as well as individuals. The high mortality rate …
Article scientifique
Crippling of Klebsiella pneumoniae virulence by metformin, N-acetylcysteine and secnidazole
INTRODUCTION: The emergence of multidrug-resistant Klebsiella pneumoniae in hospitals represents a serious threat to public health. Infections caused by Klebsiella …
Article scientifique
Variation in the morphology and effector profiles of Exserohilum turcicum isolates associated with the Northern Corn Leaf Blight of maize in Nigeria
BACKGROUND: Maize production in lowland agro-ecologies in West and Central Africa is constrained by the fungus Exserohilum turcicum, causal agent …
Article scientifique
Spatiotemporal dynamics of cholera in the Democratic Republic of the Congo before and during the implementation of the Multisectoral Cholera Elimination Plan: a cross-sectional study from 2000 to 2021
BACKGROUND: The Democratic Republic of the Congo (DRC) implemented the first strategic Multisectoral Cholera Elimination Plan (MCEP) in 2008-2012. Two …
Article scientifique
Mycorrhizal colonization and Streptomyces viridosporus HH1 synergistically up-regulate the polyphenol biosynthesis genes in wheat against stripe rust
BACKGROUND: Stripe rust is considered one of the most devastating diseases of wheat all over the world, resulting in a …
Article scientifique
Multi-omics analysis of fecal samples in colorectal cancer Egyptians patients: a pilot study
BACKGROUND: Colorectal cancer (CRC) is a public health concern and the second most common disease worldwide. This is due to …
Article scientifique
Targeting inflammasome pathway by polyphenols as a strategy for pancreatitis, gastrointestinal and liver diseases management: an updated review
Obesity, pancreatitis, cardiovascular, gastrointestinal (GI), and liver diseases have all been linked to the Western lifestyle, characterized by increased unhealthy …
Article scientifique
Retained colistin susceptibility in clinical Acinetobacter baumannii isolates with multiple mutations in pmrCAB and lpxACD operons
The progressive increase in the resistance rates to first- and second-line antibiotics has forced the reuse of colistin as last-line …
Article scientifique
Comparison of wire-guided localization (WGL) and radio-guided occult lesion localization (ROLL) in localization of non-palpable breast lesions
BACKGROUND: The number of patients with non-palpable breast lesions has increased gradually. This is because of the technological development in …
Article scientifique
Drivers of the dynamics of the spread of cholera in the Democratic Republic of the Congo, 2000–2018: An eco-epidemiological study
BACKGROUND: The dynamics of the spread of cholera epidemics in the Democratic Republic of the Congo (DRC), from east to …
Article scientifique
Evaluation of anti-quorum sensing and antibiofilm effects of secondary metabolites from Gambeya lacourtiana (De Wild) Aubr. & Pellegr against selected pathogens
BACKGROUND: Microbial infections cause serious health problems especially with the rising antibiotic resistance which accounts for about 700,000 human deaths …
Article scientifique
Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells
Abstract Background Breast cancer is a prevalent malignant tumor that affects women worldwide. The primary challenge in treating breast cancer …
Article scientifique
RETRACTED ARTICLE: Production, bioprocessing and antiproliferative activity of camptothecin from Aspergillus terreus, endophyte of Cinnamomum camphora: restoring their biosynthesis by indigenous microbiome of C. camphora
Abstract Fungal producing potency of camptothecin (CPT) raise the hope for their usage to be a platform for industrial production …
Article scientifique
Extended-spectrum β-lactamase-producing E. coli from retail meat and workers: genetic diversity, virulotyping, pathotyping and the antimicrobial effect of silver nanoparticles
Abstract Background The spread of extended-spectrum β -lactamases (ESBL) producing E. coli from food animals and the environment to humans …
Article scientifique
Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives
Abstract The current study involves the design and synthesis of a newly synthesized pyrrolo[2,3- d ]pyrimidine derivatives to contain chlorine …
Article scientifique
Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells
Abstract Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in neurodevelopmental conditions like autism spectrum disorders. …
Article scientifique
PCR diagnostics are insufficient for the detection of Diarrhoeagenic Escherichia coli in Ibadan, Nigeria
Understanding the contribution of different diarrhoeagenic Escherichia coli pathotypes to disease burden is critical to mapping risk and informing vaccine …
Article scientifique
Antibiotic resistance and virulence genes profiling of Vibrio cholerae and Vibrio mimicus isolates from some seafood collected at the aquatic environment and wet markets in Eastern Cape Province, South Africa
The current study determines the density of Vibrio spp. and isolates V. cholerae and Vibrio mimicus from fish-anatomical-sites, prawn, crab …
Article scientifique
Molecular and biological characterization of pyocyanin from clinical and environmental Pseudomonas aeruginosa
BACKGROUND: Pyocyanin is a secondary metabolite secreted by P. aeruginosa. It is a redox-active blue/green phenazine pigment that has various …