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Biologie synthétique
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Publications
7361 publication(s) trouvée(s)
Article scientifique
Going to scale—From community-based to population-wide genetic improvement and commercialized sheep meat supply in Ethiopia
Community-based breeding programs (CBBPs) have shown, at pilot scale, to be effective and beneficial in achieving genetic progress and in …
Article scientifique
Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment
BACKGROUND: Saccharomyces cerevisiae (S. cerevisiae) has been demonstrated in vitro to sensitize several breast cancer cell lines and to be …
Article scientifique
The Clinical Significance of Septin 9 and Colon Cancer Specific Antigen-2 (CCSA-2) in Colorectal Cancer
INTRODUCTION: Colorectal cancer (CRC) is a major health problem Worldwide, Egypt shows a high rate of early CRC in the …
Article scientifique
Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community
Cognitive function is an indicator for global physical and mental health, and cognitive impairment has been associated with poorer life …
Article scientifique
Quantifying morphometric and adaptive characteristics of indigenous cattle genetic resources in northwest Ethiopia
Ethiopia is the gateway of livestock genetic resources to Africa and has a wide range of altitude. It is endowed …
Article scientifique
Biological effect of bone marrow mesenchymal stem cell- derived extracellular vesicles on the structure of alveolar bone in rats with glucocorticoid-induced osteoporosis
BACKGROUND: Glucocorticoids are used for the treatment of autoimmune disorders; however, they can elicit several side effects such as osteoporosis. …
Article scientifique
Case-control study of human anthrax outbreak investigation in farta woreda, South Gondar, Northwest Ethiopia
BACKGROUND: Anthrax is a zoonotic disease caused by the Bacillus anthracis bacteria, which is one of the top five important …
Article scientifique
Surfactant nanovesicles for augmented antibacterial activity against carbapenemase resistant enterobacteriaceae and extended spectrum beta-lactamases producing bacteria: in vitro and in vivo evaluation
Abstract The ubiquitous emergence of bacterial resistance is a challenging problem in infectious diseases treatment. Recently, new research lines employed …
Article scientifique
Type 1 diabetes in low and middle-income countries - Tanzania a streak of hope
Introduction: In several of the Low and Middle Income countries , many patients with Type 1 diabetes (T1D) are most …
Article scientifique
Genetic variation and demographic history of Sudan desert sheep reveal two diversified lineages
More than 400 million sheep are raised on the African continent, the majority of which are indigenous and are primarily …
Article scientifique
LncRNA HIF1A-AS2: a potential biomarker for early diagnosis of acute myocardial infarction and predictor of left ventricular dysfunction
BACKGROUND: Rapid diagnosis of acute myocardial infarction (AMI) is the subject of many clinical studies as it enables an effective …
Article scientifique
A glucose tolerant β-glucosidase from a newly isolated Neofusicoccum parvum strain F7: production, purification, and characterization
Abstract Cellulase-producing microorganisms produce low titres of β -glucosidases with low tolerance to glucose. This study aimed to improve production, …
Article scientifique
Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma
BACKGROUND: CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 …
Article scientifique
Antibiotic resistance, pathotypes, and pathogen-host interactions in Escherichia coli from hospital wastewater in Bulawayo, Zimbabwe
This study aimed to characterise E. coli strains isolated from hospital wastewater effluent in Bulawayo, Zimbabwe, using both molecular and …
Article scientifique
Antimicrobial resistance pattern of avian pathogenic Escherichia coli with detection of extended-spectrum β-lactamase-producing isolates in broilers in east Algeria
Background and Aim: Avian pathogenic Escherichia coli (APEC) is the causative agent of colibacillosis, one of the most prevalent bacterial …
Article scientifique
A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters
Molecular farming of vaccines has been heralded as a cheap, safe and scalable production platform. In reality, however, differences in …
Article scientifique
One year overall survival of wilms tumor cases and its predictors, among children diagnosed at a teaching hospital in South Western Uganda: a retrospective cohort study
BACKGROUND: Wilms tumor (WT) is the second most common solid tumor in Africa with both low overall survival (OS) and …
Article scientifique
Fluoroquinolone resistance among fecal extended spectrum βeta lactamases positive Enterobacterales isolates from children in Dar es Salaam, Tanzania
BACKGROUND: Fluoroquinolones have been, and continue to be, routinely used for treatment of many bacterial infections. In recent years, most …
Article scientifique
New insights into the retinal microstructure-diurnal activity relationship in the African five-lined skink (Trachylepis quinquetaeniata) (Lichtenstein, 1823)
BACKGROUND: The retinae of diurnal vertebrates have characteristics. Most lizards are strictly diurnal, and their retinal morphology is still unknown. …
Article scientifique
Metabolic profiling, antioxidant, and enzyme inhibition potential of Iris pseudacorus L. from Egypt and Japan: A comparative study
Abstract Genus Iris comprises numerous and diverse phytoconstituents displaying marked biological activities. The rhizomes, and aerial parts of Iris pseudacorus …